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Table 1 Clinical characteristics of the patients

From: Amide proton transfer weighted and diffusion weighted imaging based radiomics classification algorithm for predicting 1p/19q co-deletion status in low grade gliomas

Clinical factors

Training set (n = 72)

Test set (n = 18)

p value

1p/19q co-del

1p/19q non co-del

P value

1p/19q co-del

1p/19q non co-del

p value

Number

26 (36.1)

46 (63.9)

-

7 (38.9)

11(61.1)

-

0.827

Age(years)a

42 (34–46)

43 (33–51)

0.560

52 (41–63)

43(33–59)

0.303

0.081

Sex

  

0.100

  

1.000

0.164

 Male

13 (50.0)

32 (69.6)

 

3 (42.9)

5 (45.5)

  

 Female

13 (50.0)

14 (30.4)

 

4 (57.1)

6 (54.5)

  

WHO grades

  

0.903

  

1.000

0.642

 Grade II

19 (73.1)

33 (71.7)

 

5 (71.4)

7 (63.6)

  

 Grade III

7 (26.9)

13 (28.3)

 

2 (28.6)

4 (36.4)

  

Histology

      

0.826

Oligodendroglioma

26

 

6

  

Astrocytoma

46

 

12

  

IDH

  

< 0.001

  

0.316

0.642

 Mutation

25(96.2)

27(58.7)

 

6(85.7)

6(54.5)

  

 Wildtype

1(3.8)

19(41.3)

 

1(14.3)

5(45.5)

  

Gray matter involvement

  

0.003

  

0.637

0.039

 Absent

0(0)

12(26.1)

 

2(28.6)

5(45.5)

  

 Present

26(100)

34(73.9)

 

5(71.4)

6(54.5)

  

Calcification

  

< 0.001

  

0.141

0.743

 Absent

9(34.6)

36(78.3)

 

3(42.9)

9(81.8)

  

 Present

17(65.4)

10(21.7)

 

4(57.1)

2(18.2)

  

Hemorrhage

  

1.000

  

1.000

0.316

 Absent

23(88.5)

40(87.0)

 

5(71.4)

9(81.8)

  

 Present

3(11.5)

6(13.0)

 

2(28.6)

2(18.2)

  

Tumor margin

  

0.009

  

0.316

0.820

 Indistinct

23(88.5)

27 (58.7)

 

6(85.7)

6(54.5)

  

 Sharp

3(11.5)

19(41.3)

 

1(14.3)

5(45.5)

  

Contrast enhancement

  

0.357

  

0.035

0.050

 Absent

13(50.0)

24(52.2)

 

2(28.6)

5(45.5)

  

 Present

12(46.2)

22(47.8)

 

2(28.6)

6(54.5)

  

 Not available

1(3.8)

0(0)

 

3(42.9)

0(0)

  
  1. Data are numbers of patients, with percentages in parentheses
  2. aData are medians, with inter-quartile range