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Table 2 Selected radiomic machine learning model and clinical-radiological-radiomic machine learning model performance in training and validation set

From: MRI-based machine learning models predict the malignant biological behavior of meningioma

Models

(Sequence-ROI-FS-ML)

 

Training set (n = 224)

Validation set (n = 89)

 
 

CV-AUC

(95%CI)

CV-RSD

AUC

(95%CI)

Sensitivity

(95%CI)

Specificity

(95%CI)

Delong test

Z-score

p

Grade

(T1CE-2D-LASSO-LR)

Radiomic

0.857 (0.836–0.880)

0.060

0.829 (0.786–0.863)

0.815 (0.613–0.930)

0.661 (0.529–0.774)

-1.424

0.154

CRR

  

0.821 (0.759–0.858)

0.778 (0.573–0.906)

0.629 (0.497–0.746)

  

Ki-67

(T1CE-3D-LASSO-NB)

Radiomic

0.798 (0.745–0.854)

0.090

0.752 (0.693–0.776)

0.700 (0.504–0.846)

0.780 (0.649–0.873)

0.073

0.942

CRR

  

0.753 (0.692–0.782)

0.733 (0.538–0.870)

0.763 (0.631–0.860)

  

Grade & Ki-67

(T1CE-2D-LASSO-LR)

Radiomic

0.888 (0.856–0.923)

0.051

0.904 (0.876–0.914)

0.927 (0.790–0.981)

0.604 (0.453–0.739)

0.233

0.816

CRR

  

0.906 (0.876–0.916)

0.878 (0.730–0.954)

0.708 (0.557–0.826)

  
  1. ROI, regions of Interest; FS, feature selection; ML, machine learning algorithm; 2D, two-dimensional; 3D, three-dimensional; LASSO, least absolute shrinkage and selection operator; AUC, area under the curve; RSD, relative standard deviation; NB, Naive Bayes; LR, logistic regression