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Table 1 Clinical characteristics of patients in the training and validation sets

From: Intra- and peritumoral MRI radiomics assisted in predicting radiochemotherapy response in metastatic cervical lymph nodes of nasopharyngeal cancer

Characteristics

Training set

(n = 102)

Validation set

(n = 43)

Responders

(n = 56)

Non-responders

(n = 46)

P

Responders

(n = 24)

Non-responders

(n = 19)

P

Age (mean ± SD)

45.4 ± 12.6

48.0 ± 13.4

0.310

47.5 ± 11.1

50.0 ± 12.4

0.492

Sex, n (%)

  

0.825

  

0.708

 Female

10 (17.9)

9 (19.6)

 

6 (25.0)

3 (15.8)

 

 Male

46 (82.1)

37 (80.4)

 

18 (75.0)

16 (84.2)

 

T-stage, n (%)

  

0.559

  

1.000

 T1

6 (10.7)

2 (4.3)

 

1 (4.2)

0 (0.0)

 

 T2

16 (28.6)

16 (34.8)

 

5 (20.8)

4 (21.1)

 

 T3

19 (33.9)

13 (28.3)

 

13 (54.2)

11 (57.9)

 

 T4

15 (26.8)

15 (32.6)

 

5 (20.8)

4 (21.0)

 

N-stage, n (%)

  

0.207

  

1.000

 N1

4 (7.1)

0 (0.0)

 

1 (4.2)

1 (5.3)

 

 N2

30 (53.6)

28 (60.9)

 

13 (54.1)

11 (57.9)

 

 N3

22 (39.3)

18 (39.1)

 

10 (41.7)

7 (36.8)

 

Clinical stage, n (%)

  

0.600

  

0.606

 II

2 (3.6)

0 (0.0)

 

0 (0.0)

0 (0.0)

 

 III

20 (35.7)

16 (34.8)

 

12 (50.0)

11 (57.9)

 

 IV

34 (60.7)

30 (65.2)

 

12 (50.0)

8 (42.1)

 

LN involvement, n (%)

  

0.136

  

0.757

Retropharyngeal LN

10 (17.9)

14 (30.4)

 

3 (12.5)

3 (15.8)

 

Cervical LN

46 (82.1)

32 (69.6)

 

21 (87.5)

16 (84.2)

 

GTV-ln (Gy),

median (IQR)

52.80

(46.20–60.00)

45.60

(36.07–52.35)

< 0.001*

51.50

(42.07–54.22)

41.80

(33.00–52.30)

0.047*

  1. LN lymph node, GTV-ln Lymph node gross tumor volume, IQR interquartile range. * indicates statistical significant difference
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