Table 2 The coefficients of covariates in the generalized estimating equation model for MMSE and CASI scores

Male gender

1.198

0

0.025^*

4.694

1.901

0.014^*

Education year

0.415

0.074

< 0.001^***

1.376

0.252

< 0.001^***

FDG-PET Z score

Frontal

-2.289

0.496

< 0.001^***

-9.620

1.616

< 0.001^***

PCC

1.637

0.497

0.001^**

4.676

1.794

0.009^**

Precuneus

1.434

0.657

0.029^*

4.867

2.315

0.036^*

Parietal

-0.968

0.660

0.143

-1.729

2.519

0.492

Occipital

-0.244

0.587

0.667

-1.582

1.759

0.368

Lat. temporal

1.891

0.547

0.001^**

8.733

1.938

< 0.001^***

Med. temporal

-0.011

0.266

0.967

-0.574

0.899

0.523

Measurement number, AD

2nd time

-0.847

0.632

0.180

-1.573

1.761

0.372

3rd time

-1.020

0.765

0.182

-3.177

2.242

0.157

4th time

-2.256

1.123

0.045^*

-8.341

3.017

0.006^**

5th time

-3.004

1.227

0.014^*

-15.092

3.618

< 0.001^***

6th time

-5.325

2.154

0.013^*

-21.842

4.378

< 0.001^***

Measurement number, MCI-C

2nd time

-0.339

0.590

0.565

-1.260

1.637

0.441

3rd time

-0.888

0.719

0.217

-2.628

2.045

0.199

4th time

-1.990

0.999

0.046^*

-7.282

2.780

0.009^**

5th time

-2.730

1.074

0.011^*

-15.957

3.322

< 0.001^***

6th time

-5.116

2.097

0.015^*

-22.565

4.022

< 0.001^***

Measurement number, MCI-NC

2nd time

-0.687

0.633

0.278

-1.890

2.016

0.348

3rd time

0.557

0.734

0.448

4.240

2.059

0.039^*

4th time

-0.076

0.912

0.933

0.248

2.375

0.917

5th time

-0.237

0.942

0.802

-2.682

3.169

0.397

6th time

-1.206

2.098

0.566

-8.594

3.983

0.031^*